Tijl De Bie is currently Full Professor at the University of Ghent. Before moving to Ghent, he was a Reader at the University of Bristol, where he was appointed Lecturer (Assistant Professor) in January 2007. Before that, he was a postdoctoral researcher at the KU Leuven (Belgium) and the University of Southampton. He completed his PhD on machine learning and advanced optimization techniques in 2005 at the KU Leuven. During his PhD he also spent a combined total of about 1 year as a visiting research scholar in U.C. Berkeley and U.C. Davis.

He is currently most actively interested in the formalization of subjective interestingness in exploratory data mining, and in the use of machine learning and data mining for music informatics as well as for web and social media mining. He currently holds a grant portfolio of around EUR 4M, including a prestigious ERC Consolidator Grant titled "Formalizing Subjective Interestingness in Exploratory Data Mining" (FORSIED), as well as an FWO Odysseus grant titled "Exploring Data: Theoretical Foundations and Applications to Web, multimedia, and Omics Data".